He provoked the Uddanam kidney disease crisis by various protests, which was later controlled by Government of Andhra Pradesh by constructing dialysis centres and implementing various schemes for the village. In November 2016, Pawan Kalyan announced that Jana Sena will contest in the 2019 general elections in Andhra Pradesh.  He reportedly stated that he was planning to contest from all 175 legislatures of Andhra Pradesh.  He opposed central government's move to privatise Dredging Corporation of India (DCI) on a golden platter.  Pawan lead a protest march to condolence farmers who committed suicides or migrated from the drought-prone regions of Rayalaseema.  He opposed the Telugu Desam Party Government's decision on land pooling.  Pawan Kalyan conducted a March on the historical Dowleswaram Barrage, Rajahmundry demanding Political Accountability.  Pawan Kalyan exposed the alleged unchecked mining in the reserve forest area at Vanthada Village of Prathipadu, East Godavari district.