In 2005, Vickie Guerrero made her debut as a face with her husband Eddie Guerrero and Rey Mysterio, when a storyline escalated in which Eddie promised to reveal a secret concerning Mysterio's son, Dominick. Vickie was on the July 14 SmackDown! with two of Eddie's three daughters to stop Eddie from revealing Mysterio's secret. Eddie promised not to reveal the secret should he lose to Mysterio at The Great American Bash, though that turned out to be another one of his character's trademark lies, as Eddie revealed that Dominick was really his (kayfabe) biological son. Vickie later reappeared at SummerSlam to convince Eddie to put a stop to his war with Mysterio and not to go through with the "Custody of Dominick" ladder match that night. When that failed, she cost him the match by pushing over the ladder he was on as he was about to win. After that she held down Eddie on the ground afterwards so he couldn't get up and attack Mysterio. On November 13, 2005, Eddie Guerrero died of heart failure in his Minneapolis hotel room and was found by his nephew Chavo. On-screen, this led to Rey Mysterio, Eddie's real-life friend, getting more screen time and higher profile matches, including defeating Kurt Angle and Randy Orton at WrestleMania 22 for the World Heavyweight Championship. The night before WrestleMania, Eddie was posthumously inducted into the WWE Hall of Fame, and Vickie accepted the honor on his behalf.